LL-37 is a human cathelicidin peptide used in the laboratory to investigate how natural antimicrobial mechanisms, wound healing, and immune responses function at the cellular level.
The peptide plays a key role in the innate immune system and is involved in defense against bacteria, viruses, and fungi. In research, LL-37 is often used for its influence on inflammation, tissue repair, and cell signaling.
Research findings
In vitro studies have shown that LL-37:
can stimulate cell growth and migration in wound healing;
exhibits antimicrobial activity against a wide range of pathogens;
can modulate inflammatory responses by interacting with TLR receptors;
may play a role in the regulation of immune responses and tissue repair.
Researchers are using LL-37 to study the interactions between immune cells, epithelial tissue, and microbial defense, as well as the effects on cell signaling and repair processes in vitro.
Studies:
Doss et al., 2010 (Journal of Immunology)
Vandamme et al., 2012 (Peptides)
Kahlenberg & Kaplan, 2013 (Critical Reviews in Immunology)
Research context
Applied in laboratories for research into:
antimicrobial activity
wound healing and cell regeneration
inflammation modulation and immunological pathways
Not developed for human use, consumption or medical applications.
Research Purposes Only.
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